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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-L-573655
L-573655

Chemical Structure : L-573655

CAS No.: 112507-21-8

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L-573655 (L-573, 655)

货号: PC-24470Not For Human Use, Lab Use Only.

L-573655 (L-573,655) is a specific small molecule inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), inhibits E. coli LpxC with Ki values of 24 uM and approximately 50 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

L-573655 (L-573,655) is a specific small molecule inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC), inhibits E. coli LpxC with Ki values of 24 uM and approximately 50 nM, respectively.

物理化学性质&存储条件

分子量 206.20
分子式 C10H10N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-Hydroxy-2-phenyl-4,5-dihydrooxazole-4-carboxamide

参考文献

1. Jackman JE, et al. J Biol Chem. 2000 Apr 14;275(15):11002-9.

2. Onishi HR, et al. Science. 1996 Nov 8;274(5289):980-2.

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