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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-KGDI-109
KGDI-109

Chemical Structure : KGDI-109

CAS No.: 3027146-74-0

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KGDI-109 (KGDI109)

货号: PC-26720Not For Human Use, Lab Use Only.

KGDI-109 is the first substrate-mimetic dipeptide inhibitor of P. gingivalis dipeptidyl peptidase 7 (PgDPP7) with IC50 of 53.8 uM and Ki of 25.1 uM, exerts an inhibitory effect against P. gingivalis growth with MIC of 1.56 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

KGDI-109 is the first substrate-mimetic dipeptide inhibitor of P. gingivalis dipeptidyl peptidase 7 (PgDPP7) with IC50 of 53.8 uM and Ki of 25.1 uM, exerts an inhibitory effect against P. gingivalis growth with MIC of 1.56 uM.

物理化学性质&存储条件

分子量 465.93
分子式 C22H28ClN3O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

isopropyl (S)-2-((S)-2-amino-3-(4-nitrophenyl)propanamido)-3-(4-methoxyphenyl)propanoate hydrochloride

参考文献

1. Patent JP2024008547 A 2024-01-19.

2. Aoki-Nonaka Y, et al. Sci Rep. 2026 May 8. doi: 10.1038/s41598-026-52648-8.

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