KAD-039 | Antiviral | Probechem Biochemicals

Chemical Structure : KAD-039

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KAD-039 (KAD039)

货号: PC-27979Not For Human Use, Lab Use Only.

KAD-039 is a 2', 3'-diisobutyrate-5'-ProTide prodrug with potent antiviral activity across flaviviruses, filoviruses and coronaviruses with EC50 values of 1-10 uM aginst ainst DENV and EBOV, potentially functioning through viral methyltransferase inhibition.

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生物&药学活性

KAD-039 is a 2', 3'-diisobutyrate-5'-ProTide prodrug with potent antiviral activity across flaviviruses, filoviruses and coronaviruses with EC50 values of 1-10 uM aginst ainst DENV and EBOV, potentially functioning through viral methyltransferase inhibition.

物理化学性质&存储条件

分子量	773.74
分子式	C33H44N9O11P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3S,4R,5R)-5-(4-(2-amino-4-methoxypyrimidin-5-yl)-1H-imidazol-1-yl)-2-azido-2-((((((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)tetrahydrofuran-3,4-diyl bis(2-methylpropanoate)

参考文献

1. Kyle A Davis, et al. ChemMedChem. 2026 Sep 14;21(17):e70435.

KAD-039 (KAD039)

生物&药学活性

物理化学性质&存储条件

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KAD-039 (KAD039)

生物&药学活性

物理化学性质&存储条件

参考文献

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