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Jarin-1

Chemical Structure : Jarin-1

CAS No.: 1212704-51-2

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Jarin-1 (Jarin1)

货号: PC-62257Not For Human Use, Lab Use Only.

Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana.

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5 mg ￥1880 In stock
10 mg ￥2980 In stock
25 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Jarin-1 is the first small-molecule inhibitor of JAR1 (IC50=3.8 uM) that inhibits jasmonate responses in Arabidopsis thaliana.
Jarin-1 impairs the activity of JA-Ile synthetase, thereby preventing the synthesis of the active hormone, JA-Ile, whereas closely related enzymes are not affected.
Jarin-1 is a useful chemical tool in search for missing regulatory components and further dissection of the complex jasmonate signaling networks.

物理化学性质&存储条件

分子量 471.557
分子式 C28H29N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

[1,1'-Biphenyl]-4-carboxamide,N-[(1R,5S)-1,3,4,5,6,8-hexahydro-3-(3-methoxy-1-oxopropyl)-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-9-yl]-

参考文献

1. Meesters C, et al. Nat Chem Biol. 2014 Oct;10(10):830-6.

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