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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-JSF-4536
JSF-4536

Chemical Structure : JSF-4536

CAS No.:

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JSF-4536 (JSF4536)

货号: PC-24466Not For Human Use, Lab Use Only.

JSF-4536 is a small molecule inhibitor of Mycobacterium tuberculosis methyltransferase MenG enzyme, inhibits menaquinone biosynthetic pathway, inhibits M. tuberculosis H37Rv strain with MIC of 0.78 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JSF-4536 is a small molecule inhibitor of Mycobacterium tuberculosis methyltransferase MenG enzyme, inhibits menaquinone biosynthetic pathway, inhibits M. tuberculosis H37Rv strain with MIC of 0.78 uM.

物理化学性质&存储条件

分子量 416.88
分子式 C22H22ClFN2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5′-(2-Chloro-4-fluorobenzamido)-2′-methoxy-N-methyl-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxamide

参考文献

1. Pankaj Sharma, et al. J Med Chem. 2025 Mar 13;68(5):5774-5803.

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