JP-2-197

Chemical Structure : JP-2-197

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货号: PC-26385Not For Human Use, Lab Use Only.

JP-2-197 is a fumarate-based RNF126-dependent BRD4 degrader, induces robust degradation of both long and short BRD4 isoforms in RNF126 wild-type cells but not in RNF126 knockout cells.

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JP-2-197 is a fumarate-based RNF126-dependent BRD4 degrader, induces robust degradation of both long and short BRD4 isoforms in RNF126 wild-type cells but not in RNF126 knockout cells.

物理化学性质&存储条件

分子量	657.19
分子式	C34H33ClN6O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Butene-1,4-dione, 1-[4-[2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetyl]-1-piperazinyl]-4-(4-methoxyphenyl)-, (2E)-

参考文献

1. Lim M, et al. ACS Cent Sci. 2024 May 17;10(7):1318-1331.

JP-2-197

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物理化学性质&存储条件

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JP-2-197

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物理化学性质&存储条件

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