JNK3 inhibitor 15g

Chemical Structure : JNK3 inhibitor 15g

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货号: PC-26259Not For Human Use, Lab Use Only.

JNK3 inhibitor 15g is a potent, isoform-selective JNK3 inhibitor with IC50 of 4.1 nM, 10-fold and 30-fold selective over JNK1 or JNK2.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

JNK3 inhibitor 15g is a potent, isoform-selective JNK3 inhibitor with IC50 of 4.1 nM, 10-fold and 30-fold selective over JNK1 or JNK2.
JNK3 inhibitor 15g demonstrated that it effectively alleviated TGF-β1-induced podocyte injury.

物理化学性质&存储条件

分子量	467.53
分子式	C26H25N7O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(2-(benzofuran-5-yl)-1-(2-((1-(cyclopropanecarbonyl)piperidin-3-yl) amino)pyrimidin-4-yl)-1H-imidazole-5-yl)acetonitrile

参考文献

1. Joonhong Jun, et al. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114894.