JNJ-632 |CAS:1572510-42-9 Probechem Biochemicals

Chemical Structure : JNJ-632

CAS No.: 1572510-42-9

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JNJ-632 (JNJ632)

货号: PC-35216Not For Human Use, Lab Use Only.

JNJ-632 (JNJ632) is a novel potent HBV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D.

规格	价格	库存
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

JNJ-632 (JNJ632) is a novel potent HBV capsid assembly modulator and HBV replication inhibitor with EC50 of 100-200 nM for genotypes A-D.
JNJ-632 does not show cytotoxicity for HepG2 cells (CC50>100 uM).
JNJ-632 dose-dependently reduces intracellular HBV RNA levels as well as HBe/cAg and HBsAg levels in the cell culture supernatant.

物理化学性质&存储条件

分子量	378.418
分子式	C18H19FN2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(4-fluoro-3-methylphenyl)-3-(N-(tetrahydrofuran-3-yl)sulfamoyl)benzamide

参考文献

1. Berke JM, et al. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00560-17.

JNJ-632 (JNJ632)

生物&药学活性

物理化学性质&存储条件

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JNJ-632 (JNJ632)

生物&药学活性

物理化学性质&存储条件

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