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首页-小分子抑制剂&激动剂-Epigenetics-Histone Demethylase-JB-161
JB-161

Chemical Structure : JB-161

CAS No.: 2517345-93-4

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JB-161 (JB161)

货号: PC-27266Not For Human Use, Lab Use Only.

JB-161 is a small molecule inhibitor of histone demethylase KDM5B, inhibits JFCR39 human cancer cell line panel with GI50 values in low micromolar range, shows antitumour effects.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

JB-161 is a small molecule inhibitor of histone demethylase KDM5B, inhibits JFCR39 human cancer cell line panel with GI50 values in low micromolar range, shows antitumour effects.

物理化学性质&存储条件

分子量 410.36
分子式 C14H8F6N4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4H-Pyrazolo[3,4-d]pyrimidine-4-thione, 1,5-dihydro-3-methyl-6-(trifluoromethyl)-1-[3-[(trifluoromethyl)thio]phenyl]-

参考文献

1. Hara T, et al. Cancer Med. 2026 Jun;15(6):e72058.

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