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首页-小分子抑制剂&激动剂-Others-Other Targets-Iodomethylcholine
Iodomethylcholine

Chemical Structure : Iodomethylcholine

CAS No.: 28508-22-7

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Iodomethylcholine

货号: PC-26000Not For Human Use, Lab Use Only.

Iodomethylcholine (IMC) is a highly potent non-lethal, irreversible and non-competitive TMA-generating enzyme CutC/D inhibitor with IC50 of 1.2 nM against Proteus mirabilis CutC/D, reduces TMAO levels in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Iodomethylcholine (IMC) is a highly potent non-lethal, irreversible and non-competitive TMA-generating enzyme CutC/D inhibitor with IC50 of 1.2 nM against Proteus mirabilis CutC/D, reduces TMAO levels in vivo.

物理化学性质&存储条件

分子量 356.97
分子式 C5H13I2NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethanaminium, 2-hydroxy-N-(iodomethyl)-N,N-dimethyl-, iodide (1:1)

参考文献

1. Roberts AB, et al. Nat Med. 2018 Sep;24(9):1407-1417.

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