Indapamide

Chemical Structure : Indapamide

CAS No.: 26807-65-8

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货号: PC-28028Not For Human Use, Lab Use Only.

Indapamide is a long-acting thiazide-like diuretic with vasorelaxant activities, lowers blood pressure (BP) primarily through its natriuretic diuretic effect, targets membrane-associated phospholipase N-acylphosphatidylethanolamine-specific phospholipase D (NAPE-PLD) with KD of 0.57 uM.

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生物&药学活性

Indapamide is a long-acting thiazide-like diuretic with vasorelaxant activities, lowers blood pressure (BP) primarily through its natriuretic diuretic effect, inhibits sodium-potassium-chloride cotransporter NKCC2, also targets membrane-associated phospholipase N-acylphosphatidylethanolamine-specific phospholipase D (NAPE-PLD) with KD of 0.57 uM.

物理化学性质&存储条件

分子量	365.83
分子式	C16H16ClN3O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-chloro-N-(2-methyl-1-indolinyl)-3-sulfamoylbenzamide

参考文献

1. Ma F, et al. Mol Pharmacol. 2013 Aug;84(2):286-95.

3. Chiarugi S, et al. Cell Chem Biol. 2025 Mar 20;32(3):449-462.e5.

Indapamide

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Indapamide

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