IZCZ-3 | c-MYC inhibitor | Probechem Biochemicals

Chemical Structure : IZCZ-3

CAS No.: 2223019-53-0

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IZCZ-3 (IZCZ3)

货号: PC-27086Not For Human Use, Lab Use Only.

IZCZ-3 is a potent, small molecule inhibitor of c-MYC transcription inhibitor, binds and stabilizes the c-MYC G-quadruplex.

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10 mg	￥1480	In stock
25 mg	￥2580	In stock
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生物&药学活性

IZCZ-3 is a potent, small molecule inhibitor of c-MYC transcription inhibitor, binds and stabilizes the c-MYC G-quadruplex.
IZCZ-3 provokes cell cycle arrest and apoptosis and inhibits cell growth, primarily by blocking c-MYC transcription through specific targeting of the promoter G-quadruplex structure.
IZCZ-3 effectively suppressed tumor growth in a mouse xenograft model.

物理化学性质&存储条件

分子量	715.95
分子式	C46H49N7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Ethyl-3-(1-(4-methoxyphenyl)-4,5-bis(4-(4-methylpiperazin-1-yl)phenyl)-1H-imidazol-2-yl)-9H-carbazole

参考文献

1. Hu MH, et al. J Med Chem. 2018 Mar 22;61(6):2447-2459.

IZCZ-3 (IZCZ3)

生物&药学活性

物理化学性质&存储条件

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IZCZ-3 (IZCZ3)

生物&药学活性

物理化学性质&存储条件

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