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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-ITSA-1
ITSA-1

Chemical Structure : ITSA-1

CAS No.: 200626-61-5

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ITSA-1 (ITSA1, ITSA 1)

货号: PC-42181Not For Human Use, Lab Use Only.

ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.

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25 mg ￥580 In stock
50 mg ￥880 In stock
100 mg ￥1380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ITSA-1 is a small molecule histone deacetylase (HDAC) activator that counteracts trichostatin A (TSA)-induced cell cycle arrest, histone acetylation and transcriptional activation.
ITSA-1 also suppresses acetylation of cytoplasmic alpha-tubulin as well as histones induced by hydroxamic acid-based HDAC inhibitors like TSA and SAHA.

物理化学性质&存储条件

分子量 292.1202
分子式 C13H7Cl2N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 32 mg/mL
Chemical Name/SMILES

Methanone, 1H-benzotriazol-1-yl(2,4-dichlorophenyl)-

参考文献

1. Koeller KM, et al. Chem Biol. 2003 May;10(5):397-410.

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