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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-IQM-22110
IQM-22110

Chemical Structure : IQM-22110

CAS No.: 2434630-62-1

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IQM-22110 (IQM22110)

货号: PC-26438Not For Human Use, Lab Use Only.

IQM-22110 is a selective small molecule modulator of KV4.3/KChIP channels with IC50 of 28 nM and binding affinity (Kd) of 230 nM to KChIP3, selective for KV4.3/KChIP3 over KV4.3/KChIP2 and KV4.3 channels.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

IQM-22110 is a selective small molecule modulator of KV4.3/KChIP channels with IC50 of 28 nM and binding affinity (Kd) of 230 nM to KChIP3, selective for KV4.3/KChIP3 over KV4.3/KChIP2 and KV4.3 channels.

物理化学性质&存储条件

分子量 365.81
分子式 C21H16ClNO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(2-([1,1'-biphenyl]-3-yl)acetamido)-4-chlorobenzoic acid

参考文献

1. Socuellamos PG, et al. Biochem Pharmacol. 2026 Mar 21:117921.

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