Chemical Structure : INCB13739
CAS No.: 869974-19-6
货号: PC-27071Not For Human Use, Lab Use Only.
INCB13739 (INCB-13739) is a potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with enzymatic IC50 of 3.2 nM, inhibits 11β-HSD1 in PBMCs with IC50 of 1.1 nM.
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INCB13739 (INCB-13739) is a potent, selective 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) inhibitor with enzymatic IC50 of 3.2 nM, inhibits 11β-HSD1 in PBMCs with IC50 of 1.1 nM.
| 分子量 | 467.53 | |
| 分子式 | C28H25N3O4 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-N-Methyl-5-(4-(1-(3-oxo-3H-spiro[isobenzofuran-1,3'-pyrrolidine]-1'-carbonyl)cyclopropyl)phenyl)picolinamide |
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1. Zhang C, et al. Bioorg Med Chem Lett. 2022 Aug 1;69:128782.
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