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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-IMDQ
IMDQ

Chemical Structure : IMDQ

CAS No.: 1258457-59-8

IMDQ (Imidazoquinoline, TLR7/8 agonist)

货号: PC-24366Not For Human Use, Lab Use Only.

IMDQ is a highly potent, specific TLR7/8 agonist with EC50 of 8.58 nM in human TLR7-specific reporter gene assay.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

IMDQ is a highly potent, specific TLR7/8 agonist with EC50 of 8.58 nM in human TLR7-specific reporter gene assay.

物理化学性质&存储条件

分子量 359.48
分子式 C22H25N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4- amine

参考文献

1. Shukla NM, et al. J Med Chem. 2010 Jun 10;53(11):4450-65.

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