IM-12 | GSK3β inhibitor | Probechem Biochemicals

Chemical Structure : IM-12

CAS No.: 1129669-05-1

加入收藏

IM-12 (GSK3β inhibitor IM-12, IM12)

货号: PC-42955Not For Human Use, Lab Use Only.

IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling.

规格	价格	库存
10 mg	￥680	In stock
25 mg	￥1180	In stock
50 mg	￥1980	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

IM-12 is a novel potent GSK-3β inhibitor with IC50 of 53 nM, significantly increases the β-catenin level and activates canonical Wnt signalling.
IM-12 attenuates cell proliferation of ReNcell VM cells, induces nuclear accumulation of beta-catenin.

物理化学性质&存储条件

分子量	377.4115
分子式	C22H20FN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 54.9 mg/mL
Chemical Name/SMILES	1H-Pyrrole-2,5-dione, 3-[[2-(4-fluorophenyl)ethyl]amino]-1-methyl-4-(2-methyl-1H-indol-3-yl)-

参考文献

1. Schmöle AC, et al. Bioorg Med Chem. 2010 Sep 15;18(18):6785-95.

IM-12 (GSK3β inhibitor IM-12, IM12)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

IM-12 (GSK3β inhibitor IM-12, IM12)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.