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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Parasite-IID432
IID432

Chemical Structure : IID432

CAS No.: 3094992-69-2

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IID432 (IID-432)

货号: PC-25928Not For Human Use, Lab Use Only.

IID432 (IID-432) is a highly potent inhibitor of Trypanosoma cruzi topoisomerase II (T. cruzi Topo II), shows potent activity against T. cruzi with EC50 of 8 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

IID432 (IID-432) is a highly potent inhibitor of Trypanosoma cruzi topoisomerase II (T. cruzi Topo II), shows potent activity against T. cruzi with EC50 of 8 nM.

物理化学性质&存储条件

分子量 361.41
分子式 C19H19N7O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-2-(3-cyano-1H-1,2,4-triazol-1-yl)-N-(1-(2-methylquinolin-6-yl)pyrrolidin-3-yl)acetamide

参考文献

1. René O, et al. J Med Chem. 2026 Jan 7. doi: 10.1021/acs.jmedchem.5c02459.

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