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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGFβ-Smad-IDE1
IDE1

Chemical Structure : IDE1

CAS No.: 1160927-48-9

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IDE1 (IDE 1, Inducer of definitive endoderm 1)

货号: PC-42193Not For Human Use, Lab Use Only.

IDE1 (Inducer of definitive endoderm 1) small molecule that can induce definitive endoderm from embryonic stem cells, induces the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse ESCs in vitro with EC50 of 125.5 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

IDE1 (Inducer of definitive endoderm 1) small molecule that can induce definitive endoderm from embryonic stem cells, induces the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse ESCs in vitro with EC50 of 125.5 nM.
IDE1 induces phosphorylation of Smad2 and activate TGF-β signaling.

物理化学性质&存储条件

分子量 306.3138
分子式 C15H18N2O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL
Chemical Name/SMILES

Heptanedioic acid, 1-[2-[(2-carboxyphenyl)methylene]hydrazide]

参考文献

1. Borowiak M, et al. Cell Stem Cell. 2009 Apr 3;4(4):348-58.

2. Hoveizi E, et al. J Biomed Mater Res A. 2014 Nov;102(11):4027-36.

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