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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-I2906
I2906

Chemical Structure : I2906

CAS No.: 331963-29-2

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I2906 (I 2906, I-2906)

货号: PC-45967Not For Human Use, Lab Use Only.

I2906 is a novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.

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500 mg ￥980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

I2906 is a novel isocitrate lyase (ICL) inhibitor that displays showed excellent anti-Mycobacterium tuberculosisl activities and low cytotoxicity.
I2906 shows good activity against M. tuberculosis H37Ra with MIC of 0.5 ug/ml.
I2906 significantlt reduces bacterial loads of both lungs and spleen in a murine model.

物理化学性质&存储条件

分子量 443.579
分子式 C25H37N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Quinolinecarboxylic acid, 1-ethyl-1,2-dihydro-4-hydroxy-2-oxo-, 2-(1-oxotridecyl)hydrazide

参考文献

1. Lu J, et al. Pharmacology. 2010;85(6):365-71.

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