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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-Hygromycin B
Hygromycin B

Chemical Structure : Hygromycin B

CAS No.: 31282-04-9

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Hygromycin B

货号: PC-24308Not For Human Use, Lab Use Only.

Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells, also an inhibitor of the STAT3-CCD domain, disrupts the CHI3L1-STAT3 interaction, inhibits glioblastoma both in vitro and in vivo.

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250 mg ￥480 In stock
1 g ￥880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Hygromycin B is an aminoglycoside antibiotic active against prokaryotic and eukaryotic cells, also an inhibitor of the STAT3-CCD domain, disrupts the CHI3L1-STAT3 interaction, inhibits glioblastoma both in vitro and in vivo.

物理化学性质&存储条件

分子量 527.52
分子式 C20H37N3O13
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3aS,3'R,4S,4'S,5'R,6R,6'R,7S,7aS)-4-(((1R,2S,3R,5S,6R)-3-Amino-2,6-dihydroxy-5-(methylamino)cyclohexyl)oxy)-6'-((S)-1-amino-2-hydroxyethyl)-6-(hydroxymethyl)octahydro-3aH-spiro[[1,3]dioxolo[4,5-c]pyran-2,2'-pyran]-3',4',5',7-tetraol

参考文献

1. Yu W, et al. Dev Cell. 2025 Feb 7:S1534-5807(25)00034-6.

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