HTL22562

Chemical Structure : HTL22562

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货号: PC-24984Not For Human Use, Lab Use Only.

HTL22562 is a highly potent, selective, metabolically stable antagonist of calcitonin gene-related peptide (CGRP) receptor with pKi of 10.5 (human CGRP).

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HTL22562 is a highly potent, selective, metabolically stable antagonist of calcitonin gene-related peptide (CGRP) receptor with pKi of 10.5 (human CGRP).

物理化学性质&存储条件

分子量	763.90
分子式	C40H49N11O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2′-oxo-1′,2′-dihydrospiro[piperidine-4,4′-pyrido[2,3-d][1,3]oxazine]-1-carboxamide

参考文献

1. Sarah J Bucknell, et al. J Med Chem. 2020 Jul 23;63(14):7906-7920.

HTL22562

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物理化学性质&存储条件

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HTL22562

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