HSP27 inhibitor J2 |CAS:2133499-85-9 Probechem Biochemicals

Chemical Structure : HSP27 inhibitor J2

CAS No.: 2133499-85-9

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HSP27 inhibitor J2

货号: PC-63191Not For Human Use, Lab Use Only.

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.

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2 mg	￥1580	In stock
5 mg	￥2780	In stock
10 mg	￥4280	In stock
25 mg		Get quote
100 mg		Get quote

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生物&药学活性

HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells.
HSP27 inhibitor J2 enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro.
HSP27 inhibitor J2 significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.

物理化学性质&存储条件

分子量	264.295
分子式	C13H12O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-hydroxy-2-methyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one

参考文献

1. Kim JY, et al. Sci Rep. 2018 Mar 8;8(1):4189.

2. Hwang SY, et al. Eur J Med Chem. 2017 Oct 20;139:892-900.

HSP27 inhibitor J2

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