Chemical Structure : HOIPIN-1
CAS No.:
货号: PC-35958Not For Human Use, Lab Use Only.
HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway..
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|---|---|---|---|
| 5 mg | ¥580 | In stock | |
| 10 mg | ¥880 | In stock | |
| 25 mg | ¥1380 | In stock | |
| 50 mg | ¥2180 | In stock | |
| 100 mg | Get quote |
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HOIPIN-1 (JTP-0819958, HOIP inhibitor-1) is a chemical inhibitor of linear ubiquitin chain assembly complex (LUBAC, IC50=2.8 uM), specifically generates Met1-linked linear ubiquitin chains through the ubiquitin ligase activity in HOIP, and activates the NF-kB pathway.
| 分子量 | 304.277 | |
| 分子式 | C17H13NaO4 | |
| 外观性状 | Solid | |
| 储存条件 |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Sodium (E)-2-(3-(2-methoxyphenyl)-3-oxoprop-1-en-1-yl)benzoate |
|
1. Katsuya K, et al. Biochem Biophys Res Commun. 2019 Jan 2. pii: S0006-291X(18)32846-8.
2. Katsuya K, et al. SLAS Discov. 2018 Dec;23(10):1018-1029.
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