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首页-抗体药物偶连体和PROTACs-E3 Ligase Ligand-HL389
HL389

Chemical Structure : HL389

CAS No.:

HL389 (HL-389)

货号: PC-22414Not For Human Use, Lab Use Only.

HL389 is a molecular glue acting as recruitment moiety for CRL4 DCAF11 and could be used for developed alkenyl oxindole-based PROTAC molecules.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

HL389 is a molecular glue acting as recruitment moiety for CRL4 DCAF11 and could be used for developed alkenyl oxindole-based PROTAC molecules.

物理化学性质&存储条件

分子量 498.30
分子式 C22H19BrF3NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

tert-butyl (Z)-2-(4-bromo-2-((2-oxo-6-(trifluoromethyl)indolin-3-ylidene)methyl)phenoxy)acetate

参考文献

1. Wang Y, et al. PLoS Biol. 2024 May 20;22(5):e3002550.

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