HIPK4 inhibitor 25

Chemical Structure : HIPK4 inhibitor 25

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货号: PC-28455Not For Human Use, Lab Use Only.

HIPK4 inhibitor 25 is a selective HIPK4 inhibitor with IC50 of 0.54 uM in ADP-Glo assays and cellular HIPK4 engagement EC50 of 2.8 uM, promotes HIPK4-TAX1BP1 binding, efficiently promotes HIPK4 aggregation, disrupts HIPK4 proteostasis in spermatids.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

HIPK4 inhibitor 25 is a selective HIPK4 inhibitor with IC50 of 0.54 uM in ADP-Glo assays and cellular HIPK4 engagement EC50 of 2.8 uM, promotes HIPK4-TAX1BP1 binding, efficiently promotes HIPK4 aggregation, disrupts HIPK4 proteostasis in spermatids.

物理化学性质&存储条件

分子量	339.78
分子式	C18H14ClN3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((4-Chlorophenyl)amino)-6,7-dimethoxyquinoline-3-carbonitrile

参考文献

1. Zhuang Z, et al. J Am Chem Soc. 2026 Oct 5. doi: 10.1021/jacs.6c10097.