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首页-小分子抑制剂&激动剂-Others-Other Targets-HEX-1
HEX-1

Chemical Structure : HEX-1

CAS No.: 1073-13-8

HEX-1

货号: PC-24385Not For Human Use, Lab Use Only.

HEX-1 is a valuable addition to the armamentarium against CRC, suppresses the proliferation of cancer cells and tumorigenesis via the inactivation and sensitization of PIN1.

规格 价格 库存 数量
25 mg ¥1280 In stock
50 mg ¥1980 In stock
100 mg ¥2980 In stock
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

HEX-1 is a valuable addition to the armamentarium against CRC, suppresses the proliferation of cancer cells and tumorigenesis via the inactivation and sensitization of PIN1.
HEX-1 exhibits similar functional effects as all-trans retinoic acid (atRA) but stands out by not inducing the degradation of PIN1 mRNA or protein expression, unlike biological compounds associated with atRA.
HEX-1 demonstrated the ability to induce G1/S arrest in vitro and ameliorate the progression of inflammatory CRC in mice by remodeling the gut microbiota.

物理化学性质&存储条件

分子量 124.18
分子式 C8H12O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4,4-Dimethyl-2-cyclohexen-1-one

参考文献

1. Ma Y, et al. Discov Oncol. 2025 Apr 18;16(1):565.

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