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首页-小分子抑制剂&激动剂-GPCR-Free Fatty Acid Receptor (FFAR)-Grifolic acid
Grifolic acid

Chemical Structure : Grifolic acid

CAS No.: 80557-12-6

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Grifolic acid

货号: PC-25246Not For Human Use, Lab Use Only.

Grifolic acid is a small molecule agonist of free fatty acid receptor (FFAR4/GPR120), also is a dual antagonist of voltage-gated sodium NaV1.7 and CaV2.2 channels with potent antinociceptive effects.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Grifolic acid is a small molecule agonist of free fatty acid receptor (FFAR4/GPR120), also is a dual antagonist of voltage-gated sodium NaV1.7 and CaV2.2 channels with potent antinociceptive effects.

物理化学性质&存储条件

分子量 372.51
分子式 C23H32O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,4-Dihydroxy-6-methyl-3-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)benzoic acid

参考文献

1. Zhao M, et al. Br J Pharmacol. 2025 Aug 6. doi: 10.1111/bph.70165.

2. Zhao Y, et al. Mol Med Rep. 2018;17(2):3281-3287.

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