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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Telomerase-Ginsenoside Rk1
Ginsenoside Rk1

Chemical Structure : Ginsenoside Rk1

CAS No.: 494753-69-4

Ginsenoside Rk1

货号: PC-27697Not For Human Use, Lab Use Only.

Ginsenoside Rk1 is a ginsenoside extracted from sun ginseng with anti-inflammatory and anti-tumor properties, inhibits telomerase activity in HepG2 cells.

规格 价格 库存 数量
5 mg ¥880 In stock
10 mg ¥1280 In stock
25 mg ¥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ginsenoside Rk1 is a ginsenoside extracted from sun ginseng with anti-inflammatory and anti-tumor properties, inhibits telomerase activity in HepG2 cells.
Ginsenoside Rk1 decreases expression levels of telomerase reverse transcriptase (hTERT) and c-Myc mRNA.
Ginsenoside Rk1 induces apoptosis through activation of caspases-8 and -3.
Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells by inhibiting the Jak2/Stat3 pathway.
Ginsenoside Rk1 induces phosphorylation of myosin light chain and cortactin.

物理化学性质&存储条件

分子量 767.01
分子式 C42H70O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-Dihydroxy-2-(((3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-(6-methylhepta-1,5-dien-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

参考文献

1. Kim YJ, et al. Biol Pharm Bull. 2008 May;31(5):826-30.

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