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首页-小分子抑制剂&激动剂-PI3K/Akt/mTOR Pathway-PI3K-Gilmelisib
Gilmelisib

Chemical Structure : Gilmelisib

CAS No.: 1845777-61-8

Gilmelisib

货号: PC-73420Not For Human Use, Lab Use Only.

Gilmelisib is a potent PI3K inhibitor with IC50 of <1 nM for PI3K p110α, exhibits antineoplastic acitvity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Gilmelisib is a potent PI3K inhibitor with IC50 of <1 nM for PI3K p110α, exhibits antineoplastic acitvity.

    物理化学性质&存储条件

    分子量 547.99
    分子式 C24H23ClFN5O5S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-chloro-N-(5-{3-[2-(dimethylamino)ethoxy]-4-oxo-4Hpyrido[1,2-a]pyrimidin-7-yl}-2-methoxypyridin-3-yl)-4-fluorobenzene-1-sulfonamide

    参考文献

    1. WO2017101847 A1, compound 1

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