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首页-抗体和重组蛋白-Biosimilar Antibody-Gemtuzumab
Gemtuzumab

Chemical Structure : Gemtuzumab

CAS No.: 220578-59-6

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Gemtuzumab (Anti-human SIGLEC3 mAb, human IgG4P-Kappa)

货号: PC-Ab1098Not For Human Use, Lab Use Only.

Gemtuzumab is a biosimilar directed against the extracellular domain of CD33. This product constitutes the immunogen used for the anti-Idiotype catalog numbers MAB9617 and MAB96171. The biotinylated antibody (catalog number FAB9635B) can be used in flow cytometry or various assay format to measure Siglec‑3/CD33 expression and can be detected by conjugated streptavidin. Gemtuzumab is the antibody part of Gemtuzumab ozogamicin..

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Gemtuzumab is a biosimilar directed against the extracellular domain of CD33. This product constitutes the immunogen used for the anti-Idiotype catalog numbers MAB9617 and MAB96171. The biotinylated antibody (catalog number FAB9635B) can be used in flow cytometry or various assay format to measure Siglec‑3/CD33 expression and can be detected by conjugated streptavidin. Gemtuzumab is the antibody part of Gemtuzumab ozogamicin.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Gemtuzumab; Anti-human SIGLEC3; Anti-human CD33; Anti humanSialic acid-binding Ig-like lectin 3; 220578-59-6

参考文献

1. 1, Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96. 2, Lambert J, et al. Haematologica. 2019 Jan;104(1):113-119.  3, Gottardi M, et al. Minerva Med. 2020 Oct;111(5):395-410. 4, Abaza Y, et al. Blood. 2017 Mar 9;129(10):1275-1283. 

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