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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -Gabapentin
Gabapentin

Chemical Structure : Gabapentin

CAS No.: 60142-96-3

Gabapentin

货号: PC-24642Not For Human Use, Lab Use Only.

Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker,  inhibits neuronal Ca2+ influx and reduction of neurotransmitter release, Gabapentin can antagonizes the interaction between thrombospondin-1 (TSP1 and its neuronal receptor alpha2delta1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Gabapentin is a potent, orally active P/Q type Ca2+ channel blocker,  inhibits neuronal Ca2+ influx and reduction of neurotransmitter release, Gabapentin can antagonizes the interaction between thrombospondin-1 (TSP-1) and its neuronal receptor alpha2delta1.

物理化学性质&存储条件

分子量 171.24
分子式 C9H17NO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(Aminomethyl)cyclohexyl)acetic acid

参考文献

1. Fink K, et, al. Br J Pharmacol. 2000 Jun;130(4):900-6.

2. Celikyurt IK, et, al. Neurosci Lett. 2011 Apr 1;492(2):124-8.

3. Kang S, et al. Cell Death Discov. 2018 Feb 20;4:31.

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