GW 275175X | HCMV inhibitor | Probechem Biochemicals

Chemical Structure : GW 275175X

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GW 275175X (GW275175X)

货号: PC-61947Not For Human Use, Lab Use Only.

GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.

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100 mg		Get quote

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生物&药学活性

GW 275175X is a derivative of BDCRB that displays anti-HCMV activity by inhibition of viral DNA maturation.
GW 275175X shows antiviral efficacy against AD169 laboratory strain in DNA hybridization assays with IC50 of 0.7 uM, against 10 clinically relevant HCMV isolates with IC50 of 0.16-2.21 uM, and little or no activity against HSV-1, HSV-2 and varicella zoster virus.
GW 275175X inhibits viral DNA maturation in a dose-dependent fashion.

物理化学性质&存储条件

分子量	398.034
分子式	C12H11BrCl2N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Bromo-5,6-dichloro-1-beta-D-ribofuranosyl-1H-benzimidazole

参考文献

1. Williams SL, et al. Antimicrob Agents Chemother. 2003 Jul;47(7):2186-92.

2. Underwood MR, et al. Antimicrob Agents Chemother. 2004 May;48(5):1647-51.

GW 275175X (GW275175X)

生物&药学活性

物理化学性质&存储条件

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GW 275175X (GW275175X)

生物&药学活性

物理化学性质&存储条件

参考文献

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