GW5823 (GW-5823) | CCK1 agonist | Probechem Biochemicals

Chemical Structure : GW-5823

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GW-5823 (GW5823)

货号: PC-22019Not For Human Use, Lab Use Only.

GW5823 (GW-5823) is a potent, selective orally active, gut-selective CCK1 receptor (CCK-A receptor) agonist with binding pIC50 of 7.64, ED50 of 109 nM in functional assays.

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生物&药学活性

GW5823 (GW-5823) is a potent, selective orally active, gut-selective CCK1 receptor (CCK-A receptor) agonist with binding pIC50 of 7.64, ED50 of 109 nM in functional assays.
GW5823 displays 50-fold selectivity over CCK-B receptor.

物理化学性质&存储条件

分子量	587.68
分子式	C35H33N5O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-((2H-indazol-3-yl)methyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-1-yl)-N-isopropyl-N-(4-methoxyphenyl)acetamide

参考文献

1. Richard L Elliott, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6797-801.

2. B R Henke, et al. J Med Chem. 1997 Aug 15;40(17):2706-25.

GW-5823 (GW5823)

生物&药学活性

物理化学性质&存储条件

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GW-5823 (GW5823)

生物&药学活性

物理化学性质&存储条件

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