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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Ubiquitin-conjugating Enzyme (E2)-GSK145A
GSK145A

Chemical Structure : GSK145A

CAS No.: 1609945-27-8

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GSK145A (GSK 145A, GSK-145A)

货号: PC-35105Not For Human Use, Lab Use Only.

GSK145A is a small molecule inhibitor of SUMO-conjugating enzyme E2 with IC50 of 12.5 uM, GSK145A is competitive with the sumoylation of the TRPS1 peptide substrates..

规格 价格 库存 数量
2 mg ￥2280 In stock
5 mg ￥3880 In stock
10 mg ￥5880 In stock
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纯度 & COA & 质检文件 纯度: 98.5% (HPLC) Select Batch:

生物&药学活性

GSK145A is a small molecule inhibitor of SUMO-conjugating enzyme E2 with IC50 of 12.5 uM, GSK145A is competitive with the sumoylation of the TRPS1 peptide substrates.

物理化学性质&存储条件

分子量 454.593
分子式 C23H30N6O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-5-amino-N-(4-methoxyphenyl)-2-((6-methyl-2-((2-(thiophen-2-yl)ethyl)amino)pyrimidin-4-yl)amino)pentanamide

参考文献

1. Brandt M, et al. Assay Drug Dev Technol. 2013 Jun;11(5):308-25.

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