GSK-3923868 | PI4KB inhibitor | Probechem Biochemicals

Chemical Structure : GSK-3923868

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GSK-3923868 (PI4KB inhibitor 30)

货号: PC-49466Not For Human Use, Lab Use Only.

GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs.

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生物&药学活性

GSK-3923868 (PI4KB inhibitor 30) is a potent, selective, slow-dissociating PI4KB (PI4kIII-beta) inhibitor with pKi of 9.8, >1000-fold selectivity over PI4KA, inhibits HRV viral replication in COPD BECs.

物理化学性质&存储条件

分子量	581.721
分子式	C33H39N7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(1-hydroxypropan-2-yl)-5-(5-(2-hydroxypropan-2-yl)-2-methyl-7-((3-(1-methyl-1H-imidazol-2-yl)benzyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)-N,2-dimethylbenzamide

参考文献

1. Patent WO2019141694 A1

GSK-3923868 (PI4KB inhibitor 30)

生物&药学活性

物理化学性质&存储条件

参考文献

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GSK-3923868 (PI4KB inhibitor 30)

生物&药学活性

物理化学性质&存储条件

参考文献

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