GR148672X | CES1 inhibitor | Probechem Biochemicals

Chemical Structure : GR148672X

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GR148672X (GR-148672X)

货号: PC-28548Not For Human Use, Lab Use Only.

GR148672X (GR-148672X) is a specific small molecule inhibitor of Carboxylesterase 1 (CES1)/Triacylglycerol hydrolase (TGH), significantly increases glucose limitation (GL)-induced cell death in human CRC cell linees, counters CRC tumorigenesis in vivo.

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生物&药学活性

GR148672X (GR-148672X) is a specific small molecule inhibitor of Carboxylesterase 1 (CES1)/Triacylglycerol hydrolase (TGH), significantly increases glucose limitation (GL)-induced cell death in human CRC cell linees, counters CRC tumorigenesis in vivo.
GR148672X does not inhibit the activities of pancreatic lipase, HSL ,lipoprotein lipase, and acetylcholine esterase.

物理化学性质&存储条件

分子量	340.32
分子式	C15H11F3N2O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4,4,4-Trifluoro-1-(thiophen-2-yl)-2-(2-(m-tolyl)hydrazono)butane-1,3-dione

参考文献

1. Capece D, et al. J Clin Invest. 2021;131(11):e137845.

2. Gilham D, et al. FASEB J. 2003;17(12):1685-1687.

GR148672X (GR-148672X)

生物&药学活性

物理化学性质&存储条件

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GR148672X (GR-148672X)

生物&药学活性

物理化学性质&存储条件

参考文献

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