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GPR83 agonist CPD1

Chemical Structure : GPR83 agonist CPD1

CAS No.: 924836-07-7

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GPR83 agonist CPD1

货号: PC-26013Not For Human Use, Lab Use Only.

GPR83 agonist CPD1 is a potent, selective small molecule GPR83 agonist with binding IC50 of 10 nM,  induces dose-dependent increases in intracellular Ca+2 release in CHO cells expressing mouse GPR83 with EC50 of 74 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GPR83 agonist CPD1 is a potent, selective small molecule GPR83 agonist with binding IC50 of 10 nM,  induces dose-dependent increases in intracellular Ca+2 release in CHO cells expressing mouse GPR83 with EC50 of 74 nM.
CPD1 decreases morphine antinociception in mice.

物理化学性质&存储条件

分子量 369.86
分子式 C20H16ClNO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-(2-((4-chlorobenzyl)oxy)phenyl)-6,7-dihydrothieno[3,2-b]pyridin-5(4H)-one

参考文献

1. Gomes I, et al. Mol Pharmacol. 2025 Nov 24;108(1):100092.

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