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GLPG3808

Chemical Structure : GLPG3808

CAS No.: 2346450-55-1

GLPG3808 (GLPG-3808)

货号: PC-25974Not For Human Use, Lab Use Only.

GLPG3808 is a highly potent PAPD5/7 inhibitor as effective hepatitis B surface antigen (HBsAg) suppressor with EC50 of <1 nM, inhibits HBV infection in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GLPG3808 is a highly potent PAPD5/7 inhibitor as effective hepatitis B surface antigen (HBsAg) suppressor with EC50 of <1 nM, inhibits HBV infection in vitro and in vivo.

物理化学性质&存储条件

分子量 475.92
分子式 C24H26ClNO7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-9-chloro-1-cyclopropyl-8-(3-methoxypropoxy)-5-(3-methyloxetan-3-yl)-2-oxo-1,5-dihydro-2H-chromeno[4,3-b]pyridine-3-carboxylic acid

参考文献

1. Mammoliti O, et al. J Med Chem. 2026 Jan 20. doi: 10.1021/acs.jmedchem.5c01703.

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