GDU-952 | AhR agonist | Probechem Biochemicals

Chemical Structure : GDU-952

加入收藏

GDU-952 (GDU952)

货号: PC-21481Not For Human Use, Lab Use Only.

GDU-952 (GDU952) is a novel small molecule aryl hydrocarbon receptor (AhR) agonist, activates and induces nuclear translocation of AhR.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
200 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GDU-952 (GDU952) is a novel small molecule aryl hydrocarbon receptor (AhR) agonist, activates and induces nuclear translocation of AhR.
GDU-952 (1 uM) treatment obviously increased CYP1A1 generation, induces nuclear translocation of AhR in RAW264.7 macrophages.
GDU-952 decreases IgE serum levels, to inhibit pro-inflammatory cytokines such as IL-6 and TNF-α and to induce immunoregulatory effects through restoring Th1/Th2 immune balance and promoting CD4+FOXP3+regulatory T (Treg) populations in AD skin lesions.

物理化学性质&存储条件

分子量	284.37
分子式	C17H16O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-2-(cyclopent-1-en-1-yl)-5-(2-(thiophen-3-yl)vinyl)benzene-1,3-diol

参考文献

1. Liang YH, et al. Biochem Pharmacol. 2023 Nov;217:115835.

GDU-952 (GDU952)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GDU-952 (GDU952)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.