Fresolimumab |CAS:948564-73-6 Probechem Biochemicals

Chemical Structure : Fresolimumab

CAS No.: 948564-73-6

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Fresolimumab (Anti-human TGFbeta1 mAb, human IgG4P-Kappa; GC-1008)

货号: PC-Ab1020Not For Human Use, Lab Use Only.

Fresolimumab (GC1008) is a pan-TGFβ neutralizing antibody, blocks TGFβ-mediated pSMAD signaling, and TGFβ-mediated suppression of T cells and NK cells..

规格	价格	库存
1 mg	￥3580	In stock
5 mg	￥7580	In stock
10 mg	￥12800	In stock
100 mg		Get quote

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生物&药学活性

Fresolimumab (GC1008) is a pan-TGFβ neutralizing antibody, blocks TGFβ-mediated pSMAD signaling, and TGFβ-mediated suppression of T cells and NK cells.

物理化学性质&存储条件

分子量
分子式	Human IgG4P-Kappa
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES	Fresolimumab; 948564-73-6; GC-1008; GC1008; TGF beta1; TGF beta2; TGF beta3; Pan TGF antibody

参考文献

1. 1, Grütter C, et al. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20251-6. 2, Rice LM, et al. J Clin Invest. 2015 Jul 1;125(7):2795-807. 3, Formenti SC, et al. J Immunother Cancer. 2019 Jul 11;7(1):177.

Fresolimumab (Anti-human TGFbeta1 mAb, human IgG4P-Kappa; GC-1008)

生物&药学活性

物理化学性质&存储条件

参考文献

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Fresolimumab (Anti-human TGFbeta1 mAb, human IgG4P-Kappa; GC-1008)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

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询单

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