Fosaprepitant dimeglumine

Chemical Structure : Fosaprepitant dimeglumine

CAS No.: 265121-04-8

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货号: PC-25517Not For Human Use, Lab Use Only.

Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (PC-42185), which is a potent, selective neurokinin-1 receptor (NK1R)antagonist

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Fosaprepitant dimeglumine (MK-0517) is a prodrug of Aprepitant (PC-42185), which is a potent, selective neurokinin-1 receptor (NK1R)antagonist

分子量	1004.84
分子式	C37H56F7N6O16P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol ((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)(2:1)

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2. Pranav Prasoon, et al. Indian J Pharmacol. 2016 Jul-Aug; 48(4): 394-398.

3. Navari RM. Expert Opin Investig Drugs. 2007 Dec;16(12):1977-85.