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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Forazemin
Forazemin

Chemical Structure : Forazemin

CAS No.: 325795-25-3

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Forazemin (BB-83698)

货号: PC-26790Not For Human Use, Lab Use Only.

Forazemin (BB-83698) is a potent, orally active peptide deformylase (PDF) inhibitor, shows antibacterial potency for gram-positive pathogens with MIC50 of 0.25 ug/mL and 0.06 ug/mL for Streptococcus pneumoniae and Moraxella catarrhalis.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Forazemin (BB-83698) is a potent, orally active peptide deformylase (PDF) inhibitor, shows antibacterial potency for gram-positive pathogens with MIC50 of 0.25 ug/mL and 0.06 ug/mL for Streptococcus pneumoniae and Moraxella catarrhalis.

物理化学性质&存储条件

分子量 530.67
分子式 C28H42N4O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-N-((S)-1-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)-3-cyclopentyl-2-((N-hydroxyformamido)methyl)propanamide

参考文献

1. Lofland D, et al. J Antimicrob Chemother. 2004 Apr;53(4):664-8.

2. Wise R, et al. Antimicrob Agents Chemother. 2002 Apr;46(4):1117-8.

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