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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-Flumazenil
Flumazenil

Chemical Structure : Flumazenil

CAS No.: 78755-81-4

Flumazenil (Ro 15-1788)

货号: PC-24505Not For Human Use, Lab Use Only.

Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system.

物理化学性质&存储条件

分子量 303.29
分子式 C15H14FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethyl 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

参考文献

1. Zhang LM, et al. Neuropharmacology. 2014 Jun;81:116-25.

2. Hunkeler W, et al. Nature. 1981 Apr 9;290(5806):514-6. doi: 10.1038/290514a0.

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