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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-Flibanserin
Flibanserin

Chemical Structure : Flibanserin

CAS No.: 167933-07-5

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Flibanserin (BIMT-17, BIMT-17BS)

货号: PC-27960Not For Human Use, Lab Use Only.

Flibanserin (BIMT-17, BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki of 1 nM and 49 nM, respectively, shows anti-depression and anti-anxiety effects.

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50 mg ￥1380 In stock
100 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Flibanserin (BIMT-17, BIMT-17BS) is an orally active serotonin 5-HT1A receptor agonist and 5-HT2A receptor antagonist with Ki of 1 nM and 49 nM, respectively, shows anti-depression and anti-anxiety effects.

物理化学性质&存储条件

分子量 390.41
分子式 C20H21F3N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-1H-benzimidazol-2-one

参考文献

1. Scandroglio A, et al. Pharmacol Res. 2001 Feb;43(2):179-83.

2. Podhorna J, et al. Br J Pharmacol. 2000 Jun;130(4):739-46.

3. Borsini F, et al. Naunyn Schmiedebergs Arch Pharmacol. 1995 Sep;352(3):276-82.

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