Fadeucravacitinib (ICP-488) | TYK2 inhibitor | Probechem Biochemicals

Chemical Structure : Fadeucravacitinib

加入收藏

Fadeucravacitinib (ICP-488, ICP488)

货号: PC-27425Not For Human Use, Lab Use Only.

Fadeucravacitinib (ICP-488) is a potent and selective, allosteric TYK2 inhibitor with IC50 of 5.7 nM for TYK2-JH2, blocks the signal transduction of IL-23, IL-12, type 1 IFN and other inflammatory cytokine, thereby inhibiting the pathological process of autoimmune and inflammatory diseases.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Fadeucravacitinib (ICP-488) is a potent and selective, allosteric TYK2 inhibitor with IC50 of 5.7 nM for TYK2-JH2, blocks the signal transduction of IL-23, IL-12, type 1 IFN and other inflammatory cytokine, thereby inhibiting the pathological process of autoimmune and inflammatory diseases.

物理化学性质&存储条件

分子量	425.47
分子式	C20H19D3N8O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Pyridazinecarboxamide, 6-[(cyclopropylcarbonyl)amino]-4-[[2-(methoxy-d3)-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]amino]-N-methyl-

参考文献

1. Patent WO2021180072 A1 2021-09-16.

Fadeucravacitinib (ICP-488, ICP488)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Fadeucravacitinib (ICP-488, ICP488)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.