FPR2 agonist MR-39 | FPR2 agonist | Probechem Biochemicals

Chemical Structure : FPR2 agonist MR-39

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FPR2 agonist MR-39 (MR-39)

货号: PC-20787Not For Human Use, Lab Use Only.

FPR2 agonist MR-39 is a ureidopropanamide agonist of formyl peptide receptor-2 (FPR2) with EC50 of 3.9 uM.

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生物&药学活性

FPR2 agonist MR-39 is a ureidopropanamide agonist of formyl peptide receptor-2 (FPR2) with EC50 of 3.9 uM.
MR-39 reduces IL-1β and TNF-α levels in LPS-stimulated microglial cells.
MR-39 elicits FPR2-mediated anti-inflammatory effects in rat microglia and also displays suitable pharmacokinetic characteristics.

物理化学性质&存储条件

分子量	508.95
分子式	C27H23ClF2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-((1-(3-chloro-4-fluorophenyl)cyclopropyl)methyl)-3-(4-cyanophenyl)-2-(3-(4-fluorophenyl)ureido)propanamide

参考文献

1. Ewa Trojan, et al. Cells. 2021 Jun 17;10(6):1524.

2. Stama M.L., et al. Eur. J. Med. Chem. 2017;141:703–720.

FPR2 agonist MR-39 (MR-39)

生物&药学活性

物理化学性质&存储条件

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FPR2 agonist MR-39 (MR-39)

生物&药学活性

物理化学性质&存储条件

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