FNDR-11124

Chemical Structure : FNDR-11124

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货号: PC-26221Not For Human Use, Lab Use Only.

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50 mg		Get quote
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250 mg		Get quote

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生物&药学活性

FNDR-11124 is a potent broad-spectrum inhibitor of SARS-CoV-2, influenza, KFDV and representative flaviviruses and alphaviruses, targets viral RNA-dependent RNA polymerases (RdRp) across virus families.
FNDR-11124 showed dose-dependent antiviral activity against different SARS-CoV-2 variants, including delta, kappa, and England, with an EC50 ranging from 2.4 to 3.1 μM in the Vero E6 cell by the plaque assay.
FNDR-11124 demonstrated potent antiviral activity against SARS-CoV-2 and IAV/H1N1/PR8, with EC50 values of 1.1 μM and 0.9 μM, respectively.
FNDR-11124 exhibited potent inhibitory activity against hRSV and CHIKV, as well as against DENV-2, ZIKV and WNV, and KFDV.
FNDR-11124 blocks SARS-CoV-2 and IAV infections in animal studies.

物理化学性质&存储条件

分子量	330.34
分子式	C21H14O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-hydroxy-2-(4-phenoxyphenyl)-4H-chromen-4-one

参考文献

1. Rudramurthy GR, et al. Antiviral Res. 2026 Mar 2:106382. doi: 10.1016/j.antiviral.2026.106382.

FNDR-11124

生物&药学活性

物理化学性质&存储条件

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FNDR-11124

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物理化学性质&存储条件

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