欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-抗体药物偶连体和PROTACs-ADC Cytotoxin-FL118
FL118

Chemical Structure : FL118

CAS No.: 135415-73-5

加入收藏

FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin)

货号: PC-26475Not For Human Use, Lab Use Only.

FL118 is a camptothecin derivative and payload for antibody-drug conjugates (ADCs) through topoisomerase I inhibition and proteasome-mediated degradation of anti-apoptotic proteins, also is a potent DDX5 (p68) degrader.

规格 价格 库存 数量
10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FL118 is a camptothecin derivative and payload for antibody-drug conjugates (ADCs) through topoisomerase I inhibition and proteasome-mediated degradation of anti-apoptotic proteins, also is a potent DDX5 (p68) degrader.

物理化学性质&存储条件

分子量 392.37
分子式 C21H16N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione

参考文献

1. Mathi GR, et al. Bioorg Med Chem Lett. 2025 Apr 1;118:130085.

2. Ling X, et al. J Pharm Anal. 2024 Nov;14(11):101001.

3. Tago K, et al. J Biochem. 2026 Mar 26:mvag025.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: