FIIN-4

Chemical Structure : FIIN-4

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货号: PC-28540Not For Human Use, Lab Use Only.

FIIN-4 is a first-in-class, orally active and covalent FGFR inhibitor with IC50 of 2.6 nM, 2.6 nM, 5.6 nM, 9.2 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

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生物&药学活性

FIIN-4 is a first-in-class, orally active and covalent FGFR inhibitor with IC50 of 2.6 nM, 2.6 nM, 5.6 nM, 9.2 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.

物理化学性质&存储条件

分子量	634.74
分子式	C35H38N8O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-((3-(3,5-Dimethoxyphenyl)-7-((4-(4-methylpiperazin-1-yl)phenyl)amino)-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)methyl)phenyl)acrylamide

参考文献

1. Wells S Brown, et al. Mol Cancer Ther. 2016 Sep;15(9):2096-106.

FIIN-4

生物&药学活性

物理化学性质&存储条件

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FIIN-4

生物&药学活性

物理化学性质&存储条件

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